Functions and use: It is medicine treatment raw material, indicated for the treatment of erectile dysfunction. Dissolve in water. Appearance: White powder Liquate:20c:15% Mesylate assay:99.90% Sildenafil:0.132% Heavy metals: <10ppm Water content:0.51% Residue on ignition:0.05% Mechanism:Sildenafil Mesylate, same as Sildenafil is an inhibitor of type 5 -cGMP phosphodiesterase relaxing and smoothing muscle cells of the corpus cavernosum which leads to penile erection. This relaxation may be mediated by nitric oxide via cyclic guanosine monophosphate (cGMP). Efficacy: 52% will takes effect 30 minutes after taking, 82% takes effect 1 hour after taking for Sildenafil Mesylate, suggested dosage should be 50-100mg, and 120mg is suggested for the orient. Advantage: small dosage, small side effect, dissolve in water and ethanol.
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